Results in the first two years 

The scientific aim of MedPlant is to develop new approaches and technologies for selection and sustainable use of biodiversity resources for lead discovery and to develop new plant derived leads. Results highlights fromt the first to years include two reviews of evolutionary approaches to ethnobiology (Saslis-Lagoudakis et al., 2015a; Leonti, 2015), ethnobotanical studies documenting the development of medicinal plant knowledge in Southern Italy from cumulative cultural transmission to evidence based medicine (Leonti and Staub (2015), and acculturation and loss of ethnobotanical knowledge in southern Mexico (Geck et al., submitted), new pipelines for classifying diseases and remedies in ethnomedicine and ethnopharmacology (Ernst et al., 2015; and in prep; Leonti et al., 2015; Staub et al. 2015), for investigating pharmacological similarity by charting chemical space (Buonfiglio et al., 2015; Xu et al., submitted), and exploration of DNA barcoding for authentication of herbal products (de Boer et al., 2015; Saslis-Lagoudakis et al., 2015b). In depths studies arising from individual fellows project also include publications on the development of an anti tumour drug from Thapsia garganica (Weitzel et al., 2014; Andersen et al., 2015) and a IUCN red list assessment of Anacyclis pyrethrum (Rankou et al., 2015).

(Contribution from MedPlant PIs and Fellows underlined)


Teixidor-Toneu I, Martin GJ, Puri RK, Ouhammou A, and Hawkins JA. Treating infants with frigg: linking disease aetiologies, medicinal plant use and care-seeking behaviour in southern Morocco. Journal of Ethnobiology and Ethnomedicine 2017.


Halse-Gramkow M, Ernst M (ESR5), Rønsted N, Dunn RR, Saslis-Lagoudakis CH (2016). Using evolutionary tools to search for novel psychoactive plants. Plant Genetic Resources, 1-10. doi: 10.1017/S1479262116000344.

Ernst M, Saslis-Lagoudakis CH, Grace OM, Nilsson N, Simonsen HT, Horn JW, Rønsted N. Evolutionary prediction of medicinal properties in the genus Euphorbia L. Nature Scientific Reports,

Geck M (ESR7), Reyes García AJ, Casu L, Leonti M. (2016). Acculturation and ethnomedicine: A regional comparison of medicinal plant knowledge among the Zoque of southern Mexico. Journal of Ethnopharmacology 187: 146-159. DOI: 10.1016/j.jep.2016.04.036

Staub PO, Casu L, Leonti M., 2016. Back to the roots: A quantitative survey of herbal drugs in Dioscorides’ De Materia Medica (ex Matthioli, 1568), Phytomedicine. 23, 1043-1052.

Rønsted N, Iwanycki NE (ESR4), Maldonado C, Hassemer G, Martinez K (ESR3), Saslis-Lagoudakis CH, Jäger AK, Soelberg J. The future of drug discovery – are collections needed? Accepted for publication in Scientia Danica. Series B, Biologica, The Royal Danish Academy of Sciences and Letters. 

Xu M (ESR2), Heidmarsson S, Olafsdottir ES, Buonfiglio R (ER1), Kogej T, Omarsdottir S. (2015). Secondary metabolites from cetrarioid lichens: chemotaxonomy, biological activities and pharmaceutical potential. Phytomedicine 23: 441-459. doi: 10.1016/j.phymed.2016.02.012.

Teixidor-Toneu I, Martin GJ, Ouhammou A, Puri RK, Hawkins JA, 2016. An ethnomedicinal survey of a Tashelhit-speaking community in the High Atlas, Morocco. Journal of Ethnopharmacology. 188, 96-110.

Teixidor-Toneu I, Martin GJ, Ouhammou A, Puri RK, Hawkins JA, 2016. Comprehensive dataset of the medicinal plants used by a Tashelhit speaking community in the High Atlas, Morocco. Data in Brief. 8, 516-519.


Rankou H, Ouhammou A, Taleb M, Manzanilla V (ESR13), Martin G. 2015. Anacyclus pyrethrum. The IUCN Red List of Threatened Species 2015: e.T202924A53798702.

Leonti M, Staub P (ESR8), Cabras S, Castellanos ME, Casu L (2015). From cumulative cultural transmission to evidence-based medicine: evolution of medicinal plant knowledge in Southern Italy. Frontiers in Pharmacology. Published online September 2015.

Buonfiglio R (ER1), Engkvist O, Várkonyi P, Henz A (ESR1), Vikeved E, Backlund A, Kogej T (2015). Investigating pharmacological similarity by charting chemical space. Journal of Chemical Information and Modeling. Online publication October 20th, 2015. DOI: 10.1021/acs.jcim.5b00375

Ernst M, Grace OM, Saslis-Lagoudakis CH, Nilsson N, Simonsen HT, Rønsted N (2015). Global medicinal uses of Euphorbia L. (Euphorbiaceae). Journal of Ethnopharmacology, 176:90–101. doi:10.1016/j.jep.2015.10.025

Staub PO, Geck MS, Weckerle CS, Casu L, Leonti M (2015). Classifying diseases and remedies in ethnomedicine and ethnopharmacology. Journal of Ethnopharmacology 174:514-519. doi:10.1016/j.jep.2015.08.051

Saslis-Lagoudakis CH, Bruun-Lund S, Iwanycki NE (ESR4), Seberg O, Petersen G, Jäger AK, Rønsted N (2015b). Identification of common horsetail (Equisetum arvense L.: Equisetaceae) using thin layer chromatography versus DNA barcoding. Scientific Reports 5, 11942. DOI: 10.1038/srep11942.

Andersen TB, López CQ, Manczak T, Martinez K (ESR3) and Simonsen HT (2015). Thapsigargin—From Thapsia L. to Mipsagargin. Molecules 20, 6113-6127. DOI:10.3390/molecules20046113. PDF Version: